VALIDATION OF A QUESTIONNAIRE ON BELIEFS ABOUT INHALED TREATMENT IN PATIENTS WITH COPD

Clinical Research Results Abstract Introduction: to carry out a validation study of a questionnaire that assesses beliefs about inhaled treatment in patients with COPD who regularly use these therapies (the CCTI-Questionnaire).Methods: Descriptive, cross-sectional study of 260 patients with COPD included in the electronic medical records database from five primary healthcare centres. Sample size was calculated for a 10-item questionnaire for an estimated Cronbach’s alpha of 0.70, with a 95% confidence level. Study participants were selected by systematic random sampling. Variables: the 10 item CCTI-Questionnaire (personal and telephone interview during pandemic), time for completion, age, sex, educational level, spirometric severity (GOLD criteria), number of exacerbations (previous year), characteristics of inhaled treatment, current smoking habit.Results: Mean age 71,5 (8,12) years; 198 males (75,6%), low educational level 55,6% of the sample; 21,1% are active smokers; mild stage severity 50,8%; average number of exacerbations in the previous year 0.65 (1.05); 36,8% have been using inhalers for more than 10 years.The mean (SD) global score was 6.43 (2), median 7, out of a maximum of 10 points. A score of 5 or more was obtained by 69.5% of patients. The mean (SD) completion time was 3.11 (1.53) minutes. The internal consistency of the questionnaire (Cronbach’s alpha) scored 0.613.In Factor analysis (Kaiser-Meyer-Olkin test, 0.74; Bartlett’s sphericity test, p <0.0001) 3 factors were identified that explained 47.58% of the total variance. Factor 1 about the use of inhalers (Items 4, 5, 7, 8, 9); Factor 2, about the effects of inhalers (Items 2, 3, 6); Factor 3, about the objectives of the inhaled treatment (Items 1, 10).Discussion: The 10-items CCTI-Questionnaire 2.0 has demostrated acceptable psychometric properties regarding feasibility, reliability and content validity. Research Idea Abstract Service Development & Evaluation Abstract Declaration of Interest I am reporting that there is no potential competing interest reported by the authors. References and Clinical Trial Registry Information Keywords: EPOC (COPD), Conocimiento y creencias de la medicación por el paciente (Patient Medication Knowledge), Tratamiento inhalado (Nebulizers and Vaporizers)